Accuracy and Safety of Laparoscopic Lymphadenectomy: An Experimental Prospective Randomized Study
Identifieur interne : 000873 ( France/Analysis ); précédent : 000872; suivant : 000874Accuracy and Safety of Laparoscopic Lymphadenectomy: An Experimental Prospective Randomized Study
Auteurs : Dominique Lanvin [France] ; Abdou Elhage [France] ; Bénédicte Henry [France] ; Eric Leblanc [France] ; Denis Querleu [France] ; Alice Delobelle-Deroide [France]Source :
- Gynecologic Oncology [ 0090-8258 ] ; 1997.
Abstract
Introduction.The goal of this study was to investigate the accuracy and safety of bilateral pelvic and paraaortic lymphadenectomy performed via transperitoneal laparoscopy (LS) compared to laparotomy (LT) in a porcine model. Materials and methods.Fifteen adult, female hogs underwent LS and 15 underwent LT. A complete pelvic and paraaortic lymphadenectomy was performed in each animal by an experienced surgeon. Lymph nodes were counted by a pathologist in each case. Operative times were reviewed and included all procedures performed. The intraoperative complications were noted. Four weeks after the lymphadenectomy, the animals underwent exploratory laparotomy, and intraperitoneal adhesions were quantified. Results.Thirty animals were evaluable. The average total number of lymph nodes retrieved by LS was 16.9 ± 3.8, which was not statistically (P= 0.77) different from 16.5 ± 4.9 nodes in LT. The average operating time in LT was 60 ± 16 min compared with 128 ± 24 min in LS. Twenty-eight animals were evaluable for adhesion formation. The average adhesion scores observed in anterior abdominal wall (P= 0.0006), paraaortic (P= 0.0005), right (P= 0.015), and left (P= 0.0324) iliac areas after LS were uniformly lower than after LT. Discussion.This study indicates that laparoscopic pelvic and paraaortic lymphadenectomy is a safe and effective procedure. The node yield is similar for both approaches. The transperitoneal laparoscopy pelvic and paraaortic lymphadenectomy may not induce the degree of adhesion formation associated with laparotomy.
Url:
DOI: 10.1006/gyno.1997.4823
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 005099
- to stream Istex, to step Curation: 005099
- to stream Istex, to step Checkpoint: 004129
- to stream Main, to step Merge: 00C349
- to stream Main, to step Curation: 00BB76
- to stream Main, to step Exploration: 00BB76
- to stream France, to step Extraction: 000873
Links to Exploration step
ISTEX:AC22D6613C7B2C537694BCE6825F62749779BFBCLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Accuracy and Safety of Laparoscopic Lymphadenectomy: An Experimental Prospective Randomized Study</title><author><name sortKey="Lanvin, Dominique" sort="Lanvin, Dominique" uniqKey="Lanvin D" first="Dominique" last="Lanvin">Dominique Lanvin</name></author><author><name sortKey="Elhage, Abdou" sort="Elhage, Abdou" uniqKey="Elhage A" first="Abdou" last="Elhage">Abdou Elhage</name></author><author><name sortKey="Henry, Benedicte" sort="Henry, Benedicte" uniqKey="Henry B" first="Bénédicte" last="Henry">Bénédicte Henry</name></author><author><name sortKey="Leblanc, Eric" sort="Leblanc, Eric" uniqKey="Leblanc E" first="Eric" last="Leblanc">Eric Leblanc</name></author><author><name sortKey="Querleu, Denis" sort="Querleu, Denis" uniqKey="Querleu D" first="Denis" last="Querleu">Denis Querleu</name></author><author><name sortKey="Delobelle Deroide, Alice" sort="Delobelle Deroide, Alice" uniqKey="Delobelle Deroide A" first="Alice" last="Delobelle-Deroide">Alice Delobelle-Deroide</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:AC22D6613C7B2C537694BCE6825F62749779BFBC</idno><date when="1997" year="1997">1997</date><idno type="doi">10.1006/gyno.1997.4823</idno><idno type="url">https://api.istex.fr/document/AC22D6613C7B2C537694BCE6825F62749779BFBC/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">005099</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">005099</idno><idno type="wicri:Area/Istex/Curation">005099</idno><idno type="wicri:Area/Istex/Checkpoint">004129</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">004129</idno><idno type="wicri:doubleKey">0090-8258:1997:Lanvin D:accuracy:and:safety</idno><idno type="wicri:Area/Main/Merge">00C349</idno><idno type="wicri:Area/Main/Curation">00BB76</idno><idno type="wicri:Area/Main/Exploration">00BB76</idno><idno type="wicri:Area/France/Extraction">000873</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Accuracy and Safety of Laparoscopic Lymphadenectomy: An Experimental Prospective Randomized Study</title><author><name sortKey="Lanvin, Dominique" sort="Lanvin, Dominique" uniqKey="Lanvin D" first="Dominique" last="Lanvin">Dominique Lanvin</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Département hospitalo–universitaire de recherche expérimentale, Faculté de Médecine, University of Lille, 1, place de Verdun, 59000, Lille</wicri:regionArea><placeName><region type="region" nuts="2">Hauts-de-France</region><region type="old region" nuts="2">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Elhage, Abdou" sort="Elhage, Abdou" uniqKey="Elhage A" first="Abdou" last="Elhage">Abdou Elhage</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Département hospitalo–universitaire de recherche expérimentale, Faculté de Médecine, University of Lille, 1, place de Verdun, 59000, Lille</wicri:regionArea><wicri:noRegion>59000, Lille</wicri:noRegion><wicri:noRegion>Lille</wicri:noRegion></affiliation></author><author><name sortKey="Henry, Benedicte" sort="Henry, Benedicte" uniqKey="Henry B" first="Bénédicte" last="Henry">Bénédicte Henry</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Département hospitalo–universitaire de recherche expérimentale, Faculté de Médecine, University of Lille, 1, place de Verdun, 59000, Lille</wicri:regionArea><placeName><region type="region" nuts="2">Hauts-de-France</region><region type="old region" nuts="2">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Leblanc, Eric" sort="Leblanc, Eric" uniqKey="Leblanc E" first="Eric" last="Leblanc">Eric Leblanc</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Centre Oscar Lambret, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Querleu, Denis" sort="Querleu, Denis" uniqKey="Querleu D" first="Denis" last="Querleu">Denis Querleu</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Département hospitalo–universitaire de recherche expérimentale, Faculté de Médecine, University of Lille, 1, place de Verdun, 59000, Lille</wicri:regionArea><wicri:noRegion>59000, Lille</wicri:noRegion><wicri:noRegion>Lille</wicri:noRegion></affiliation></author><author><name sortKey="Delobelle Deroide, Alice" sort="Delobelle Deroide, Alice" uniqKey="Delobelle Deroide A" first="Alice" last="Delobelle-Deroide">Alice Delobelle-Deroide</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Centre Oscar Lambret, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Gynecologic Oncology</title><title level="j" type="abbrev">YGYNO</title><idno type="ISSN">0090-8258</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1997">1997</date><biblScope unit="volume">67</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="83">83</biblScope><biblScope unit="page" to="87">87</biblScope></imprint><idno type="ISSN">0090-8258</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0090-8258</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Introduction.The goal of this study was to investigate the accuracy and safety of bilateral pelvic and paraaortic lymphadenectomy performed via transperitoneal laparoscopy (LS) compared to laparotomy (LT) in a porcine model. Materials and methods.Fifteen adult, female hogs underwent LS and 15 underwent LT. A complete pelvic and paraaortic lymphadenectomy was performed in each animal by an experienced surgeon. Lymph nodes were counted by a pathologist in each case. Operative times were reviewed and included all procedures performed. The intraoperative complications were noted. Four weeks after the lymphadenectomy, the animals underwent exploratory laparotomy, and intraperitoneal adhesions were quantified. Results.Thirty animals were evaluable. The average total number of lymph nodes retrieved by LS was 16.9 ± 3.8, which was not statistically (P= 0.77) different from 16.5 ± 4.9 nodes in LT. The average operating time in LT was 60 ± 16 min compared with 128 ± 24 min in LS. Twenty-eight animals were evaluable for adhesion formation. The average adhesion scores observed in anterior abdominal wall (P= 0.0006), paraaortic (P= 0.0005), right (P= 0.015), and left (P= 0.0324) iliac areas after LS were uniformly lower than after LT. Discussion.This study indicates that laparoscopic pelvic and paraaortic lymphadenectomy is a safe and effective procedure. The node yield is similar for both approaches. The transperitoneal laparoscopy pelvic and paraaortic lymphadenectomy may not induce the degree of adhesion formation associated with laparotomy.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Hauts-de-France</li><li>Nord-Pas-de-Calais</li></region><settlement><li>Lille</li></settlement></list><tree><country name="France"><region name="Hauts-de-France"><name sortKey="Lanvin, Dominique" sort="Lanvin, Dominique" uniqKey="Lanvin D" first="Dominique" last="Lanvin">Dominique Lanvin</name></region><name sortKey="Delobelle Deroide, Alice" sort="Delobelle Deroide, Alice" uniqKey="Delobelle Deroide A" first="Alice" last="Delobelle-Deroide">Alice Delobelle-Deroide</name><name sortKey="Elhage, Abdou" sort="Elhage, Abdou" uniqKey="Elhage A" first="Abdou" last="Elhage">Abdou Elhage</name><name sortKey="Henry, Benedicte" sort="Henry, Benedicte" uniqKey="Henry B" first="Bénédicte" last="Henry">Bénédicte Henry</name><name sortKey="Leblanc, Eric" sort="Leblanc, Eric" uniqKey="Leblanc E" first="Eric" last="Leblanc">Eric Leblanc</name><name sortKey="Querleu, Denis" sort="Querleu, Denis" uniqKey="Querleu D" first="Denis" last="Querleu">Denis Querleu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/France/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000873 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000873 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= France
|étape= Analysis
|type= RBID
|clé= ISTEX:AC22D6613C7B2C537694BCE6825F62749779BFBC
|texte= Accuracy and Safety of Laparoscopic Lymphadenectomy: An Experimental Prospective Randomized Study
}}
| This area was generated with Dilib version V0.6.31. |  |